Anthony HemingwayDirector
Dominic WestDet. James "Jimmy" McNulty
John DomanWilliam A. Rawls
Frankie FaisonComm. Ervin H. Burrell
Wood HarrisAvon Barksdale
Domenick LombardozziDet. Thomas "Herc" Hauk
Deirdre LovejoyRhonda Pearlman
Wendell PierceDet. William "Bunk" Moreland
Lance ReddickLt. Cedric Daniels
Andre RoyoBubbles
Sonja SohnDet. Shakima "Kima" Greggs
J.D. WilliamsPreston "Bodie" Broadus
Seth GilliamSgt. Ellis Carver
Clarke PetersDet. Lester Freamon
Jim True-FrostDet. Roland "Prezbo" Pryzbylewski
Michael WilliamsOmar Little
Corey RobinsonDet. Leander Sydnor
Robert WisdomHoward "Bunny" Colvin
Aidan GillenThomas "Tommy" Carcetti
Jamie HectorMarlo Stanfield
Chad ColemanDennis "Cutty" Wise
Isiah Whitlock Jr.State Sen. R. Clayton "Clay" Davis
Glynn TurmanMayor Clarence V. Royce
Reginald CatheyNorman Wilson
Jermaine CrawfordDuquan "Dukie" Weems
Maestro HarrellRandy Wagstaff
Julito McCullumNamond Brice
Tristan WildsMichael Lee
Robert ChewJoseph "Proposition Joe" Stewart
Susan DuvallAssistant Principal Marcia Donnelly
Dravon JamesGrace Sampson
Edward NorrisDet. Edward Norris
Michael KostroffMaurice "Maury" Levy
Delaney WilliamsSgt. Jay Landsman
Sam CoppolaFormer Mayor "Young Tony"
Gregory WilliamsDet. Michael Crutchfield
Brian WilsonDet. Vernon Holley
Cleo PizanaChief of Staff Coleman Parker
Susan RomeAsst. State's Atty. Ilene Nathan
Frederick StrotherState Delegate Odell Watkins
Stacie DavisMs. Duquette
Dan DeLucaDavid Parenti
Dion GrahamState's Attorney Rupert Bond
Greg AinsworthRichard Switowski
Nathan CorbettDonut
Thuliso DingwallKenard
Edward GreenSpider
Jeffrey LorenzoKarim Williams
Daniel Robertson IIIShaun Williams
Tony DevonMr. Shopper